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FCN2

May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.
Protein class

Plasma proteins

Predicted location

Secreted

Single cell type specificity

Cell type enriched (Hepatic stellate cells)

Immune cell specificity

Immune cell enhanced (classical monocyte, intermediate monocyte)

Cell line specificity

Not detected

Interaction

Homotrimer (PubMed:17215869). Interacts with elastin. Interacts with MASP1 and MASP2. Interacts with CR1.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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