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GNB4

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. [provided by RefSeq, Jul 2008]
Protein class

Disease related genes, Human disease related genes, RAS pathway related proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Kupffer cells, Microglial cells, Hofbauer cells, Macrophages)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HDLM-2)

Interaction

G proteins are composed of 3 units, alpha, beta and gamma.

Molecular function

Transducer

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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