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GNRHR
Monoclonal antibodies against gonadotropin releasing hormone (GnRH) receptor induce cellular apoptosis of various cancer cells expressing this surface receptor. The monoclonal antibodies can serve as anti-cancer agents for the treatment of cancer in humans, and can function as analogs of GnRH to affect regulation of reproductive functions or fertility in humans.
Protein class
Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Inhibitory neurons, Excitatory neurons, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, IF, IHC
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
- Anti-Human GNRHR Recombinant Antibody (TAB-325CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
- Human Anti-GNRHR Antibody, mRNA (TAB-325CL-mRNA)
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- Species Reactivity: Human
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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For Research Use Only. Not For Clinical Use.