Intracellular
Cell type enhanced (Early spermatids, Spermatocytes, Spermatogonia)
Low immune cell specificity
Cell line enhanced (HEL)
Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly (PubMed:19369198, PubMed:19427217). Interacts with PLK1, NEDD1 and gamma-tubulin (PubMed:19029337). Interacts with EML3 (phosphorylated at 'Thr-881') (PubMed:30723163).
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For Research Use Only. Not For Clinical Use.