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HOXC9

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12.
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Distal tubular cells, Melanocytes, Skeletal myocytes, Granulosa cells, Proximal tubular cells, Spermatogonia, Fibroblasts, Smooth muscle cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AN3-CA, HDLM-2, HEK93)

Interaction

Interacts with Geminin/GMNN, which inhibits transcriptional activity.

Molecular function

Developmental protein, DNA-binding

More Types Infomation

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