Enzymes
Intracellular, Membrane (different isoforms)
Cell type enhanced (Excitatory neurons, Glandular and luminal cells, Langerhans cells, Basal keratinocytes, Suprabasal keratinocytes)
Not detected in immune cells
Cell line enhanced (A-431, ASC TERT1, HaCaT, HSkMC, hTCEpi)
Interacts with IL1RAP; the association is enhanced by IL36B indicative for an functional signaling complex and inhibited by IL36RN (By similarity).
Hydrolase, Receptor
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For Research Use Only. Not For Clinical Use.