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ITGB8
ITGB8 (Integrin Subunit Beta 8) is a Protein Coding gene. Diseases associated with ITGB8 include Hypoplastic Right Heart Syndrome and Arteriovenous Malformation. Among its related pathways are Beta-Adrenergic Signaling and Blood-Brain Barrier Pathway: Anatomy. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and extracellular matrix protein binding. An important paralog of this gene is ITGB3.
Protein class
Cancer-related genes
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Glandular and luminal cells, Endometrial ciliated cells, Oligodendrocyte precursor cells)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Cell line enhanced (AF22, EFO-21, RPTEC TERT1, WM-115)
Interaction
Heterodimer of an alpha and a beta subunit (PubMed:1918072). Beta-8 (ITGB8) associates with alpha-V (ITGAV) to form ITGAV:ITGB8 (PubMed:1918072, PubMed:22278742). ITGAV:ITGB8 interacts with TGFB1 (PubMed:22278742).
Molecular function
Integrin, Receptor
More Types Infomation
- A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer (MHC-CN0920)
-
- Class: Class I
- Antigen: ITGB8
- Antigen Species: Human
- Peptide: ALMEQQHYV
- Conjugate: Unconjugated
- FITC-A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer (MHC-CN0919)
-
- Class: Class I
- Antigen: ITGB8
- Antigen Species: Human
- Peptide: ALMEQQHYV
- Conjugate: FITC
- APC-A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer (MHC-CN0918)
-
- Class: Class I
- Antigen: ITGB8
- Antigen Species: Human
- Peptide: ALMEQQHYV
- Conjugate: APC
- PE-A*02:01/Human ITGB8 (ALMEQQHYV) MHC Tetramer (MHC-CN0917)
-
- Class: Class I
- Antigen: ITGB8
- Antigen Species: Human
- Peptide: ALMEQQHYV
- Conjugate: PE
- A*02:01/Human ITGB8 (ALMEQQHYV) MHC Pentamer (MHC-YF505)
-
- Class: Class I
- Antigen: ITGB8
- Antigen Species: Human
- Peptide: ALMEQQHYV
- Conjugate: Unlabeled, Biotin, R-PE, APC
- Recombinant Mouse Anti-Human ITGB8 Antibody (MOB-2027MZ)
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
- Mouse Anti-ITGB8 Recombinant Antibody; Fab Fragment (HPAB-0401-WJ-F(E)) (HPAB-0401-WJ-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-ITGB8 Recombinant Antibody; Fab Fragment (HPAB-0400-WJ-F(E)) (HPAB-0400-WJ-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-ITGB8 Recombinant Antibody (HPAB-0401-WJ) (HPAB-0401-WJ)
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-ITGB8 Recombinant Antibody (HPAB-0400-WJ) (HPAB-0400-WJ)
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-ITGB8 Recombinant Antibody; scFv Fragment (HPAB-0401-WJ-S(P)) (HPAB-0401-WJ-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-ITGB8 Recombinant Antibody; scFv Fragment (HPAB-0400-WJ-S(P)) (HPAB-0400-WJ-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Chicken Anti-ITGB8 Polyclonal IgY (BRD-0303MZ)
-
- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.