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IVL
Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Suprabasal keratinocytes, Squamous epithelial cells, Urothelial cells, Club cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HaCaT, RT4, SK-BR-3)
Interaction
Directly or indirectly cross-linked to cornifelin (CNFN).
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Rat, Human
- Type: IgG
- Application: FC, IHC-P, WB
- Human Anti-IVL Antibody (clone SY5), mRNA (FAMAB-1209CQ-mRNA)
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- Species Reactivity: Canine, Pig, Primate, Human
- Human Anti-IVL Recombinant Antibody (clone SY5) (FAMAB-1209CQ)
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- Species Reactivity: Canine, Pig, Primate, Human
- Type: Human IgG1
- Application: IP, WB, IF, IHC
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- Species Reactivity: Human
- Application: IHC-P, WB
- Mouse Anti-IVL Recombinant Antibody (clone 39D9) (MOB-2479z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, IHC, IP
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IHC, FC
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- Derivation: Rabbit
- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.