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KEL
This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.
Protein class
Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Erythroid cells, Oligodendrocytes, Squamous epithelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HEL, K-562)
Interaction
Heterodimer with XK; disulfide-linked.
Molecular function
Blood group antigen, Hydrolase, Metalloprotease, Protease
More Types Infomation
- Human Anti-Kel Antibody (clone MIMA-8), mRNA (FAMAB-1373CQ-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human
- Application: WB
- Human Anti-Kel Recombinant Antibody (clone MIMA-8) (FAMAB-1373CQ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: FC
- Mouse Anti-KEL Recombinant Antibody (clone 24B1) (MOB-3054z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, IHC
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, IHC, IP, WB
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: Haemagglutination
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- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: Haemagglutination
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- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: Haemagglutination
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For Research Use Only. Not For Clinical Use.