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KIF21A
This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants.
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cone photoreceptor cells, Bipolar cells, Inhibitory neurons)
Immune cell specificity
Group enriched (memory CD8 T-cell, gdT-cell, naive CD8 T-cell, memory CD4 T-cell, MAIT T-cell, NK-cell, T-reg)
Cell line specificity
Cell line enriched (SH-SY5Y)
Interaction
Interacts (via residues 1146-1167) with KANK1 (via ankyrin repeats 1-5) and KANK2 (via ankyrin repeats 1-5).
Molecular function
Motor protein
More Types Infomation
- Recombinant Anti-Human KIF21A Antibody scFv Fragment (MOB-3065z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FuncS
- Recombinant Anti-Human KIF21A Antibody Fab Fragment (MOB-3065z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, Nert, FuncS
- Recombinant Anti-Human KIF21A Antibody (MOB-3065z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, FuncS
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For Research Use Only. Not For Clinical Use.