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LGR6

This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding.
Protein class

G-protein coupled receptors, Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Basal squamous epithelial cells, Cardiomyocytes, Breast myoepithelial cells, dendritic cells)

Immune cell specificity

Group enriched (gdT-cell, memory CD8 T-cell, naive CD8 T-cell)

Cell line specificity

Cell line enhanced (A549, CAPAN-2, HaCaT, HeLa)

Molecular function

G-protein coupled receptor, Receptor, Transducer

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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