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LYPD3

C4.4A (LYPD3) has been identified as a cancer- and metastasis-associated internalizing cell surface protein that is expressed in non-small cell lung cancer (NSCLC), with particularly high prevalence in the squamous cell carcinoma (SCC) subtype.
Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Suprabasal keratinocytes, Squamous epithelial cells, Syncytiotrophoblasts, Urothelial cells, Basal keratinocytes)

Immune cell specificity

Immune cell enhanced (naive CD4 T-cell)

Cell line specificity

Cell line enhanced (CAPAN-2, HaCaT, MCF7, RT4, SK-BR-3)

Interaction

Binds laminin-1 and laminin-5. Interacts with LGALS3 (By similarity). Interacts with AGR2 and AGR3.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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