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MNX1
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein class
Disease related genes, Human disease related genes, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Enteroendocrine cells, Intestinal goblet cells, Undifferentiated cells, Proximal enterocytes, Paneth cells, Distal enterocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AN3-CA, BEWO, EFO-21, HEK93, RPMI-8226, SCLC-21H)
Molecular function
DNA-binding
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: IP, WB
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IP
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For Research Use Only. Not For Clinical Use.