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MYBL1
Protein class
Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (dendritic cells, NK-cells, T-cells, Plasma cells, Spermatocytes)
Immune cell specificity
Immune cell enhanced (gdT-cell, MAIT T-cell)
Cell line specificity
Cell line enhanced (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, Daudi, HBF TERT88)
Interaction
Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.
Molecular function
Activator, DNA-binding
More Types Infomation
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- Species Reactivity: Human
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.