Disease related genes, Human disease related genes
Intracellular
Cell type enhanced (Cone photoreceptor cells)
Low immune cell specificity
Low cell line specificity
Interacts (via IQ domains) with CALM (PubMed:9490638). Interacts with RHOA (PubMed:26529257). Interacts (via Rho-GAP domain) with ROBO1; this inhibits the interaction with RHOA and the stimulation of RHOA GTPase activity, and thereby increases the levels of active RHOA (PubMed:26529257).
Actin-binding, Calmodulin-binding, GTPase activation, Motor protein, Myosin
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For Research Use Only. Not For Clinical Use.