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NEB
This giant muscle protein may be involved in maintaining the structural integrity of sarcomeres and the membrane system associated with the myofibrils. Binds and stabilize F-actin
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Skeletal myocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (Karpas-707, RH-30, U-266/70)
Interaction
Monomer and homooligomer (PubMed:23615443). Interacts with TTN/titin (PubMed:12482578). Interacts with SVIL (PubMed:18639526). Interacts (via nebulin repeats 160-164) with DES (PubMed:23615443).
Molecular function
Actin-binding, Muscle protein
More Types Infomation
- Mouse Anti-NEB Recombinant Antibody (clone 40B3) (MOB-3135z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, IP, IF, ELISA
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For Research Use Only. Not For Clinical Use.