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NMNAT2
This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Inhibitory neurons, Excitatory neurons, Oligodendrocyte precursor cells, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HSkMC, SCLC-21H, SuSa, U-2197, U-87 MG)
Interaction
Monomer.
Molecular function
Nucleotidyltransferase, Transferase
More Types Infomation
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- Species Reactivity: Human
- Application: FC, ICC/IF, IHC-P, WB
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For Research Use Only. Not For Clinical Use.