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OTUB2
Ubiquitin thioesterase OTUB2 is an enzyme that in humans is encoded by the OTUB2 gene. Hydrolase can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. It mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains.
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Group enriched (Late spermatids, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (GAMG, Karpas-707, OE19, RPTEC TERT1)
Molecular function
Hydrolase, Protease, Thiol protease
More Types Infomation
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- Species Reactivity: Human
- Type: IgG
- Application: ELISA, ICC/IF, IF
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For Research Use Only. Not For Clinical Use.