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POU1F1

This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class

Disease related genes, Human disease related genes, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Not detected

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Interacts with PITX1 (PubMed:26612202). Interacts with LHX3 (PubMed:26612202). Interacts with ELK1 (PubMed:26612202).

Molecular function

Activator, DNA-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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