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PPARGC1A
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism.
Protein class
Cancer-related genes
Predicted location
Intracellular
Single cell type specificity
Group enriched (Inhibitory neurons, Excitatory neurons, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (A-431)
Interaction
Homooligomer (PubMed:10713165). Interacts with MYBBP1A; inhibits MYBBP1A transcriptional activation (By similarity). Interacts with PRDM16, LPIN1 and PML (By similarity). Interacts (via LXXLL motif) with RORA and RORC (via AF-2 motif); activates RORA and RORC transcriptional activation (By similarity). Interacts with LRPPRC (PubMed:17050673). Interacts with FOXO1 (By similarity).
Molecular function
Activator, RNA-binding
More Types Infomation
Related Signaling Pathways
PPAR Signaling Pathway
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, ELISA
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, FC, WB
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- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB
- Mouse Anti-PPARGC1A Recombinant Antibody (clone 1G8) (VS3-XY1283)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.