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PTK7

This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Protein class

Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular, Membrane, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Early spermatids, Endometrial stromal cells)

Immune cell specificity

Immune cell enriched (plasmacytoid DC)

Cell line specificity

Low cell line specificity

Interaction

Interacts with CTNNB1.

Molecular function

Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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