Enzymes, Metabolic proteins
Intracellular, Membrane (different isoforms)
Cell type enhanced (Langerhans cells, Macrophages, dendritic cells, Oligodendrocyte precursor cells, Inhibitory neurons)
Immune cell enhanced (neutrophil, plasmacytoid DC)
Cell line enhanced (hTERT-RPE1, HUVEC TERT2, NB-4, TIME)
Monomer. Isoform 2: Homodimer. Can form oligomers. Dimerization is increased by oxidative stress and decreased by EGFR. Isoform 2 interacts with GRB2 (By similarity).
Hydrolase, Protein phosphatase
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For Research Use Only. Not For Clinical Use.