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RAB31
Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002 [PubMed 11784320]).[supplied by OMIM, Jul 2009]
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Kupffer cells, Macrophages, Langerhans cells, monocytes, Syncytiotrophoblasts, Oligodendrocyte precursor cells, Cytotrophoblasts)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Cell line enhanced (GAMG)
Interaction
Interacts with OCRL. Interacts with NGFR (By similarity). Interacts (in GDP-bound form) with RIN3 and GAPVD1, which function as guanine exchange factors (GEF). Interacts (in GTP-bound form) with EEA1. Interacts with EGFR. Interacts (in GTP-bound form) with APPL2; interaction contributes to or enhances recruitment of APPL2 to the phagosomes; interaction enhances Fc-gamma receptor-mediated phagocytosis through PI3K/Akt signaling in macrophages (By similarity).
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.