Disease related genes, RAS pathway related proteins
Intracellular
Cell type enhanced (Muller glia cells, T-cells, dendritic cells, Excitatory neurons, Plasma cells)
Immune cell enhanced (T-reg)
Group enriched (HDLM-2, JURKAT, MOLT-4)
Homodimer (PubMed:23908768). Forms a signaling complex with DGKZ and HRAS (PubMed:11257115). Interacts with F-actin (PubMed:12839994). Interacts with SKAP1 (PubMed:17658605).
Guanine-nucleotide releasing factor
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For Research Use Only. Not For Clinical Use.