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SHANK1

Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Inhibitory neurons, Excitatory neurons, Horizontal cells, Oligodendrocyte precursor cells, Bipolar cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (REH, THP-1, U-138 MG, U-2 OS, U-87 MG, U-937)

Interaction

May homomultimerize via its SAM domain (By similarity). Interacts with the C-terminus of SSTR2 via the PDZ domain. Interacts with IGSF9, SHARPIN, SPTAN1, HOMER1 and DLGAP1/GKAP isoforms 1 and 2 (By similarity). Part of a complex with DLG4/PSD-95 and DLGAP1/GKAP (By similarity). Interacts with BAIAP2. Interacts with HOMER1 and HOMER3 (By similarity).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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