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SLC18A1
The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine. See also SLC18A2 (MIM 193001).
Protein class
FDA approved drug targets, Metabolic proteins, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enriched (Enteroendocrine cells)
Immune cell specificity
Immune cell enhanced (non-classical monocyte)
Cell line specificity
Cell line enriched (SH-SY5Y)
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, FC
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.