Products

10-FnIII anti-N (SFN-L020)

The tenth fibronectin type III domain (10Fn3) that bound SARS N protein was isolated from the library using mRNA Display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=1.7 nM) for SARS N protein as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      

Specifications
Scaffold Name
10-FnIII
Origin
Fibronectin
Core Structure
β-sandwich of 7 β-strands
Variable Regions
2–3 Loops
Target
SARS N protein
Species Reactivity
SARS
Expression Host
E. coli
Affinity Constant
1.7 nM
Applications
ELISA; immunohistochemistry; Microscopy; Flow Cytometer; Western Blotting; Functional Study
Target
Alternative Names
Fibronectin; 10-FnIII; sars9a; nucleocapsid protein; N protein; N
Entrez Gene ID
1489678
UniProt ID
P59595

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Send Inquiry Now!
Name:
* Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "biolabs"(case insensitive) as verification code.
Contact Us to Order
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-871-5806    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2017 Creative-Biolabs All Rights Reserved