APC-A*24:02/Human PSA (CYASGWGSI) MHC Tetramer (CAT#: MHC-LC040)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of PSA-derived peptide of CYASGWGSI sequence covering 153-161 and A*24:02 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*24:02
  • Class
  • Class I
  • Antigen
  • PSA
  • Antigen Species
  • Human
  • Peptide
  • CYASGWGSI
  • Range
  • 153-161
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
  • Alternative Names
  • KLK3; kallikrein related peptidase 3; APS; PSA; hK3; KLK2A1

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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