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APC-B*27:05/Human CACNA1D (SRRWRRWNR) MHC Tetramer (CAT#: MHC-LC1590)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of CACNA1D-derived peptide of SRRWRRWNR covering 513-521 and B*27:05 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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  • Gene Expression
  • Datasheet
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  • COA
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20215/1525_G2_6_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20215/47850_B_9_5.jpg
Figure 3 Colon
Figure 3 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20215/47850_A_8_3.jpg
Figure 4 Liver
Figure 4 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20215/47850_A_8_4.jpg
Figure 5 Pancreas
Figure 5 Pancreas
(Pancreatic endocrine cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20215/47850_A_3_3.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20215/47850_A_8_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20215/47850_A_4_6.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/20215/47850_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (HMC-1, RPMI-8226, SK-BR-3)
Figure 9 RNA cell line category: Cell line enhanced (HMC-1, RPMI-8226, SK-BR-3)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157388-CACNA1D

Specifications

  • Allele
  • B*27:05
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • CACNA1D
  • Antigen Species
  • Human
  • Peptide
  • SRRWRRWNR
  • Range
  • 513-521
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • CACNA1D; calcium voltage-gated channel subunit alpha1 D; CACH3; CACN4; PASNA; SANDD; Cav1.3; CCHL1A2; CACNL1A2

Downloads

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See other products for "CACNA1D"

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC1589 PE-B*27:05/Human CACNA1D (SRRWRRWNR) MHC Tetramer FCM
MHC-LC1591 BV421-B*27:05/Human CACNA1D (SRRWRRWNR) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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