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APC-B*41:03/Human HNRNPC (AEMYGSVTEHPSPSPL) MHC Tetramer (CAT#: MHC-LC1581)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HNRNPC-derived peptide of AEMYGSVTEHPSPSPL covering 102-117 and B*41:03 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


See more MHC Tetramer products for HNRNPC
Specific Inquiry
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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5223/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75755/1894_G2_3_selected.jpg
Normal Tissue
Figure 3 IHC staining of human prostate
Figure 3 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows strong nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5223/ihc_selected.jpg
Figure 4 IHC staining of human tonsil
Figure 4 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows strong nuclear positivity in germinal center cells and non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75755/159385_A_5_8_selected.jpg
Figure 5 Liver
Figure 5 Liver
(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5223/13358_A_9_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5223/13358_A_9_5.jpg
Figure 7 Testis
Figure 7 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Peritubular cells Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51075/124984_A_6_6.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51075/124984_A_7_8.jpg
Figure 9 Colon
Figure 9 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51075/124984_A_9_3.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Figure 10 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000092199-HNRNPC

Specifications

  • Allele
  • B*41:03
  • Class
  • Class I
  • Antigen
  • HNRNPC
  • Antigen Species
  • Human
  • Peptide
  • AEMYGSVTEHPSPSPL
  • Range
  • 102-117
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.
  • Alternative Names
  • HNRNPC; heterogeneous nuclear ribonucleoprotein C (C1/C2); C1; C2; HNRNP; HNRPC; SNRPC

Downloads

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See other products for "HNRNPC"

Recombinant Antibody

CAT Product Name Application Type
MOB-0611CT Recombinant Mouse anti-Human HNRNPC Monoclonal antibody (5G5) ELISA, ICC/IF, IHC-P, IP, WB
MRO-0760-CN Rabbit Anti-HNRNPC Recombinant Antibody (clone CBACN-281) WB, IF, IHC, IP, FC Rabbit IgG
ZG-0741J Rabbit Anti-HNRNPC Recombinant Antibody (clone 9G1) ELISA, WB, IHC, IF, FC, IP Rabbit IgG
VS1-YJ99 Mouse Anti-HNRNPC Recombinant Antibody (clone 4F4) ELISA, IF, IHC-P, IP Mouse IgG1
VS3-CJ476 Rabbit Anti-HNRNPC Recombinant Antibody (VS3-CJ476) WB, ICC, IF, IHC, IP, FC Rabbit IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC1580 PE-B*41:03/Human HNRNPC (AEMYGSVTEHPSPSPL) MHC Tetramer FCM
MHC-LC1582 BV421-B*41:03/Human HNRNPC (AEMYGSVTEHPSPSPL) MHC Tetramer FCM

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1646 Rabbit Anti-HNRNPC Recombinant Antibody (clone DS1646AB) WB, IHC-P, ICC Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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