Anti-ER-a36 (clone SNGmBI)-MB-vc-duocarmycin ADC (CAT#: ADC-241CL)
This ADC product is composed of an anti-ER-a36 antibody (clone SNGmBI) conjugated via MB-vc linker to duocarmycin(Ab-MB-vc-duocarmycin). It has demonstrated a response in treatment by a MOA (Mechanism of Action) of binding to DNA minor groove and causing DNA damage as a alkylating agent.
Specific Inquiry
Specifications
- Antibody Overview
- Anti-ER-a36 Monoclonal Antibody SNGmBI (mlgG2b)
- Clone
- SNGmBI
- Antibody Isotype
- mlgG2b
- Linker
- MB-VC
- Drug
- duocarmycin
- Drug Class/Description
- Class: Duocarmycins
Dsecription: Duocarmycins belong to the minor-groove-binding DNA-alkylating agents (DNA MGBA). The natural duocarmycins are isolated from the culture broth of Streptmyces sp and a series of derivatives has also been synthesized.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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