The anti-AChR antibody P90-131 targets acetylcholine receptor of which the high-level re-expression can occur after birth following denervation, including denervating neuromuscular diseases. The antibody can be used in the treatment of rhabdomyosarcoma.
Figure 1 P90-131 of concentrated supernatants specifically binds to the fetal AChR.
Specificity of P90-131 was tested for binding to purified extracellular domains of human AChR subunits using Western blot. Proteins are visualized by Coomassie staining (upper panel).
Vrolix, K., Fraussen, J., Molenaar, P. C., Losen, M., Somers, V., Stinissen, P., ... & Martinez-Martinez, P. (2010). The auto-antigen repertoire in myasthenia gravis. Autoimmunity, 43(5-6), 380-400.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-33 | Recombinant Anti-AChR Antibody | ELISA, WB, IF, FuncS | IgG |
PABC-007 | Rat Anti-AChR Recombinant Antibody (clone mAb192) | WB, FuncS | Rat IgG2b, κ |
MOB-082CQ | Mouse Anti-AChR Recombinant Antibody (clone mAb192) | ELISA, WB, Block | Mouse IgG2a, κ |
VS-0723-CJ5 | Mouse Anti-AChR Recombinant Antibody (clone 35) | Inhib, IHC | Mouse IgG |
VS-0723-CJ38 | Human Anti-AChR Recombinant Antibody (clone 131) | ELISA, WB, IF, Inhib, DB | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-33-F(E) | Recombinant Anti-AChR Antibody Fab Fragment | IP, FuncS | Fab |
PFBC-007 | Rat Anti-AChR Recombinant Antibody (clone mAb192); Fab Fragment | WB, FuncS | Rat IgG2b, κ |
PFBZ-007 | Rat Anti-AChR Recombinant Antibody (clone mAb198); Fab Fragment | WB, ELISA | Rat IgG |
FAMAB-0001WJ-F(E) | Human Anti-AChR Recombinant Antibody (clone 587); Fab Fragment | RIA, IP, IF | Human Fab |
FAMAB-0002WJ-F(E) | Human Anti-AChR Recombinant Antibody (clone 637); Fab Fragment | RIA, IP, IF | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBC-007 | Rat Anti-AChR Recombinant Antibody (clone mAb192); scFv Fragment | WB, FuncS | Rat scFv |
PSBZ-007 | Rat Anti-AChR Recombinant Antibody (clone mAb198); scFv Fragment | WB, ELISA | Rat scFv |
FAMAB-0223-YC-S(P) | Rat Anti-AChR Recombinant Antibody (clone mAb 192); scFv Fragment | FuncS | Rat scFv |
FAMAB-0224-YC-S(P) | Rat Anti-AChR Recombinant Antibody (clone mAb 195); scFv Fragment | FuncS | Rat scFv |
FAMAB-0029WJ-S(P) | Human Anti-AChR Recombinant Antibody (clone MH6); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0637CLV | Anti-Human AChR Recombinant Antibody (P90-65) | RIA, IF | Fully Human antibody |
TAB-0638CLV-F(E) | Human Anti-AChR Recombinant Antibody; Fab Fragment (TAB-0638CLV-F(E)) | ELISA | Human Fab |
TAB-0639CLV-F(E) | Human Anti-AChR Recombinant Antibody; Fab Fragment (TAB-0639CLV-F(E)) | ELISA | Human Fab |
TAB-0638CLV-S(P) | Human Anti-AChR Recombinant Antibody; scFv Fragment (TAB-0638CLV-S(P)) | ELISA | Human scFv |
TAB-0639CLV-S(P) | Human Anti-AChR Recombinant Antibody; scFv Fragment (TAB-0639CLV-S(P)) | ELISA | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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