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Anti-APCS Therapeutic Antibody (TAB-047CL)

Recombinant Human monoclonal antibody expressed in CHO binding to Human APCS. Anti-SAP antibody treatment is clinically feasible because circulating human SAP can be depleted in patients by the bis-D-proline compound, CPHPC4, thereby enabling injected anti-SAP antibodiess to reach residual SAP in the amyloid deposits. The unprecedented capacity of this novel combined therapy to eliminate amyloid deposits should be applicable to all forms of systemic and local amyloidosis.      

Specifications
Host
Human
Derivation
Mouse
Type
Antibody
Species Reactivity
Human
Related Disease
Systemic amyloidosis
Target
Alternative Names
APCS; amyloid P component, serum; SAP; PTX2; HEL-S-92n; serum amyloid P-component; pentaxin-related; 9.5S alpha-1-glycoprotein
Entrez Gene ID
325
UniProt ID
P02743

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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