Anti-Human CCL23 Recombinant Antibody Fab Fragment (MOR08389_g3-23_g3j) (CAT#: TAB-1497CL-F(E))
This antibody can bind to human CCL21 (hCCL21) and it can be used in the treatment and/or prevention of human diseases and disorders, particularly those of a fibrotic nature.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human pancreas
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/ihc_selected.jpg
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/91004_B_9_5.jpg
(Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/91004_B_9_5.jpg
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/91004_A_7_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/91004_A_7_3.jpg
Figure 4 Liver
(Hepatocytes Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/91004_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/91004_A_7_4.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/91004_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/91004_A_9_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/91004_A_4_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42015/91004_A_4_6.jpg
Figure 7 RNA cell line category: Group enriched (HEL, THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000274736-CCL23
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000274736-CCL23
Specifications
- Host Species
- Human
- Type
- Fully human antibody
- Specificity
- Human
- Clone
- MOR08389_g3-23_g3j
- Related Disease
- Pulmonary fibrosis (e.g. IPF), chronic obstructive pulmonary disease (COPD), hepatic fibrosis, rheumatoid arthritis, congestive heart failure, chronic renal disease and so on.
Target
- Alternative Names
- CCL21; chemokine (C-C motif) ligand 21; ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21; C-C motif chemokine 21; beta chemokine exodus-4; secondary lymphoid tissue chemokine; Efficient Chemoattractant for Lymphocytes; small inducible cytokine subfamily A (Cys-Cys),j.
- Gene ID
- 6368
- UniProt ID
- O00587
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1497CL | Anti-Human CCL23 Recombinant Antibody (MOR08389_g3-23_g3j) | FuncS | Fully human antibody |
| TAB-1497CL-S(P) | Anti-Human CCL23 Recombinant Antibody scFv Fragment (MOR08389_g3-23_g3j) | FuncS | Fully human antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1109CT | Mouse Anti-CCL23 Recombinant Antibody (clone BOU232) | ELISA | Mouse IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-180CQ | Mouse Anti-CCL23 Recombinant Antibody (clone CBL004) | Neut, WB | Mouse IgG1 |
| NEUT-181CQ | Mouse Anti-CCL23 Recombinant Antibody (clone CBL691) | WB, Neut | Mouse IgG1 |
| NEUT-182CQ | Mouse Anti-CCL23 Recombinant Antibody (clone CBL486) | WB, CyTOF, ICFC, Neut | Mouse IgG1 |
| NEUT-183CQ | Mouse Anti-CCL23 Recombinant Antibody (clone G3_4G10.3) | ELISA, Neut, WB | Mouse IgG1, κ |
| NEUT-184CQ | Mouse Anti-CCL23 Recombinant Antibody (clone CBL968) | WB, FC, Neut, ELISA | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0507 | Hi-Affi™ Rabbit Anti-CCL23 Recombinant Antibody (clone DS507AB) | WB, IF | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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