This antibody is capable of binding specifically to the human CD151 protein, which can be used as a medicament for the prophylactic and/or therapeutic treatment of cancers and in diagnostic methods or kits for diseases associated with overexpression of the CD151 protein.
Figure 1 shows the analysis, by flow cytometry, of the recognition of CD151 by the murine antibody 214B2 on the surface of NIH 3T3-CD151 cells.
Figure 2 shows the results of evaluation of the specificity of antibodies 20386, 205H8, 211F3 and 21482 by Western blot.
Figure 3 illustrates the anti-tumour activity of anti-CD151 monoclonal antibodies in the PC3 prostate tumour xenograft model.
The PC3 cells were grafted into Swiss Nude mice (n=6) by the subcutaneous route. Five days after grafting of the cells, the mice receive, by the i.p. route, a challenge dose of 2 mg/mouse of the antibody under test followed by two administrations per week of a dose of 1 mg/mouse of that antibody. The tumour volume is determined by the formula π/6×length×width×thickness.
Figure 4 shows the effect of the anti-CD151 antibodies on platelet functions with Platelet aggregation.
Figure 5 shows the effect of anti-CD151 antibodies on the tumour growth, in vivo, of NCI-H441 cells.
Figure 6 illustrates the in vivo activity of the c214B2[IgG1] Mab on tumor growth of PC3, an androgen-independent prostate cell line.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1605CL | Anti-Human CD151 Recombinant Antibody (c203B6) | ELISA, FC, WB | Chimeric antibody (mouse/human) |
TAB-1606CL | Anti-Human CD151 Recombinant Antibody (c214B2) | ELISA, FC, WB, Block, FuncS | Chimeric antibody (mouse/human) |
TAB-1605CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (c203B6) | ELISA, FC, WB | Chimeric antibody (mouse/human) |
TAB-1605CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (c203B6) | ELISA, FC, WB | Chimeric antibody (mouse/human) |
TAB-1606CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (c214B2) | ELISA, FC, WB, Block, FuncS | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1607CL | Anti-Human CD151 Recombinant Antibody (Humanized 203B6) | FC, FuncS, WB | Humanized antibody |
TAB-1607CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (Humanized 203B6) | FC, FuncS, WB | Humanized antibody |
TAB-1608CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (Humanized 214B2) | FC, FuncS, WB | Humanized antibody |
TAB-1607CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (Humanized 203B6) | FC, FuncS, WB | Humanized antibody |
TAB-1608CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (Humanized 214B2) | FC, FuncS, WB | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1601CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (203B6) | FC, FuncS | |
TAB-1602CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (205H8) | FC, FuncS | |
TAB-1603CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (211F3) | FC, FuncS | |
TAB-1604CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (214B2) | FC, FuncS | |
TAB-1601CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (203B6) | FC, FuncS |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-285CQ | Mouse Anti-CD151 Recombinant Antibody (clone 50-6) | FC, ICC, WB, Block | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0533 | Hi-Affi™ Rabbit Anti-CD151 Recombinant Antibody (clone DS533AB) | WB, IHC, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0212-CN | Mouse Anti-CD151 Recombinant Antibody (clone TS151r) | FC, IP, IHC, IF, Inhib, WB | Mouse IgG |
HPAB-0213-CN | Mouse Anti-CD151 Recombinant Antibody (clone TS151) | IF, FuncS, IB, WB, FC, IHC, IP | Mouse IgG |
HPAB-0214-CN | Mouse Anti-CD151 Recombinant Antibody (clone 9B) | WB, Co-IP, IF, IHC, Inhib, FuncS, FC, ELISA | Mouse IgG1 |
FAMAB-1034CQ | Human Anti-CD151 Recombinant Antibody (clone 11G5a) | IP, FC, FuncS, IHC | Human IgG1 |
VS3-XY208 | Mouse Anti-CD151 Recombinant Antibody (clone 3G1) | WB, IP, IF, IHC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0212-CN-S(P) | Mouse Anti-CD151 Recombinant Antibody (clone TS151r); scFv Fragment | WB, FC, IHC, IP | Mouse scFv |
HPAB-0213-CN-S(P) | Mouse Anti-CD151 Recombinant Antibody (clone TS151); scFv Fragment | WB, FC, IHC, IP | Mouse scFv |
HPAB-0214-CN-S(P) | Mouse Anti-CD151 Recombinant Antibody (clone 9B); scFv Fragment | WB, ELISA, IHC, IF, Co-IP | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0212-CN-F(E) | Mouse Anti-CD151 Recombinant Antibody (clone TS151r); Fab Fragment | WB, FC, IHC, IP | Mouse Fab |
HPAB-0213-CN-F(E) | Mouse Anti-CD151 Recombinant Antibody (clone TS151); Fab Fragment | WB, FC, IHC, IP | Mouse Fab |
HPAB-0214-CN-F(E) | Mouse Anti-CD151 Recombinant Antibody (clone 9B); Fab Fragment | WB, ELISA, IHC, IF, Co-IP | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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