Anti-Human CD3 Recombinant Antibody Fab Fragment (VH1/VK1) (CAT#: TAB-085LC-F(E))

TAB-085LC is a recombinant monoclonal antibody targeting CD3. It is a humanized antibody with potential applications in treating autoimmune disorders, infectious diseases, and transplant rejection. This antibody is valuable in pharmaceutical use due to its humanized and de-immunized framework regions (FRs), which minimize the risk of a HAHA/HAMA response. Additionally, it enhances cell signaling activities to achieve positive immunological effects, while preserving cell-surface binding and preventing improper disulfide bond formation. Furthermore, it improves pharmaceutical stability. TAB-085LC-F(E) antibody is the Fab fragment antibody form of TAB-085LC antibody. Fab fragments, the antigen-binding domains of an antibody molecule, consist of two amino acid chains composed of VH+CH1 and VL+CL domains.


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Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Clone
  • VH1/VK1
  • Applications
  • ELISA, FC
  • Related Disease
  • Autoimmune Disorders, infectious diseases, and Transplant rejection

Target

  • Alternative Names
  • CD3; CD3 T-Cell Co-receptor;CD3D; CD3E; CD3G

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone VH1/VK1"

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Humanized Antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-0417CL Chimeric Anti-Human CD3 Recombinant Antibody ELISA, FC, FuncS Chimeric (mouse/human)
TAB-071LC-S(P) Anti-Human CD3 Recombinant Antibody scFv Fragment ELISA Chimeric antibody (mouse/human)
TAB-072LC-S(P) Chimeric Anti-Human CD3 Recombinant Antibody scFv Fragment ELISA Chimeric antibody (mouse/human)
TAB-071LC-F(E) Anti-Human CD3 Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)
TAB-072LC-F(E) Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)

Blocking Antibody

CAT Product Name Application Type
NEUT-339CQ Mouse Anti-CD3 Recombinant Antibody (clone SPV-T3b) FC, Block, IHC-Fr, IF, WB Mouse IgG2a
NEUT-340CQ Mouse Anti-CD3 Recombinant Antibody (clone UCHT1) FC, IHC-Fr, IHC-P, ICC, IP, WB, Activ, Block Mouse IgG1, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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