Anti-Human CD46 Recombinant Antibody (mPA7) (CAT#: TAB-272LC)
Recombinant monoclonal antibody to CD46. mPA7 is a mouse monoclonal antibody that can be potentially used in the treatment of cancers.
Specific Inquiry
Inhib
Figure 1 is a graph that shows inhibition of LnCaP prostatic carcinoma cell growth in a monolayer by mPA7.
WB
Figure 2 is a graph which shows the epitope that mPA7 binds is disulfide bond dependent.
FuncS
Figure 3 is a graph shows the effect of mPA7 and Mab-ZAP (an anti-IgG conjugate to saporin) on the growth of human prostate tumor cells LNCaP.
Specifications
- Immunogen
- hPED
- Host Species
- Mouse
- Specificity
- Human
- Clone
- mPA7
- Applications
- FuncS, Inhib, WB
- Related Disease
- Cancers
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay, Inhibition, Western Blot.
Target
- Alternative Names
- The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
- Gene ID
- 4179
- UniProt ID
- P15529
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone mPA7"
See other products for "CD46"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1132z | Mouse Anti-CD46 Recombinant Antibody (clone 12A2) | WB, ELISA, FC, IF, IHC, IP, FuncS | Mouse IgG1, κ |
| MOB-0504CT | Mouse Anti-CD46 Recombinant Antibody (clone NFN-369) | FC, IP, WB | Mouse IgG1 |
| HPAB-0524-CN | Human Anti-CD46 Recombinant Antibody (HPAB-0524-CN) | WB, ELISA, FC, IHC, IP | Human IgG1 |
| HPAB-0525-CN | Human Anti-CD46 Recombinant Antibody (HPAB-0525-CN) | WB, ELISA, FC, IHC, IP | Human IgG1 |
| ZG-0134U | Rabbit Anti-CD46 Recombinant Antibody (clone 7D12) | ELISA, WB, IHC | Rabbit IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0288CL | Human Anti-CD46 Recombinant Antibody (TAB-0288CL) | RIA, ELISA, FC | Human IgG1 |
| TAB-0289CL | Human Anti-CD46 Recombinant Antibody (TAB-0289CL) | RIA, ELISA, FC | Human IgG1 |
| TAB-0290CL | Human Anti-CD46 Recombinant Antibody (TAB-0290CL) | RIA, ELISA, FC | Human IgG1 |
| TAB-267LC-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-267LC-S(P)) | IHC, ELISA | Human scFv |
| TAB-267LC-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-267LC-F(E)) | IHC, ELISA | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-268LC | Mouse Anti-CD46 Recombinant Antibody (TAB-268LC) | Cyt, FuncS | Mouse IgG |
| TAB-269LC | Mouse Anti-CD46 Recombinant Antibody (TAB-269LC) | Cyt, FuncS | Mouse IgG |
| TAB-268LC-S(P) | Mouse Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-268LC-S(P)) | FC, ELISA | Mouse scFv |
| TAB-269LC-S(P) | Mouse Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-269LC-S(P)) | FC, ELISA | Mouse scFv |
| TAB-272LC-S(P) | Anti-Human CD46 Recombinant Antibody scFv Fragment (mPA7) | IHC |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-270LC | Human Anti-CD46 Recombinant Antibody (TAB-270LC) | Cyt, FuncS | Humanized IgG1, κ |
| TAB-271LC | Human Anti-CD46 Recombinant Antibody (TAB-271LC) | Cyt, FuncS | Humanized IgG1, κ |
| TAB-270LC-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-270LC-S(P)) | FC, ELISA | Humanized scFv |
| TAB-271LC-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (TAB-271LC-S(P)) | FC, ELISA | Humanized scFv |
| TAB-270LC-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (TAB-270LC-F(E)) | FC, ELISA | Humanized Fab |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-385CQ | Mouse Anti-CD46 Recombinant Antibody (clone TRA-2-10) | FC, Block, IF, IP | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0564 | Hi-Affi™ Rabbit Anti-CD46 Recombinant Antibody (clone DS564AB) | ICC, IHC-P, WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0524-CN-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0524-CN-S(P)) | WB, ELISA, FC, IHC, IP | Human scFv |
| HPAB-0525-CN-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0525-CN-S(P)) | WB, ELISA, FC, IHC, IP | Human scFv |
| HPAB-0366-YC-S(P) | Human Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0366-YC-S(P)) | ELISA, FC | Humanized scFv |
| HPAB-0368-YC-S(P) | Mouse Anti-CD46 Recombinant Antibody; scFv Fragment (HPAB-0368-YC-S(P)) | ELISA, FC | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0524-CN-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0524-CN-F(E)) | WB, ELISA, FC, IHC, IP | Human Fab |
| HPAB-0525-CN-F(E) | Human Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0525-CN-F(E)) | WB, ELISA, FC, IHC, IP | Human Fab |
| HPAB-0367-YC-F(E) | Mouse Anti-CD46 Recombinant Antibody (clone SC1.N122); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0368-YC-F(E) | Mouse Anti-CD46 Recombinant Antibody; Fab Fragment (HPAB-0368-YC-F(E)) | ELISA, FC | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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