Anti-Human CEACAM6 Therapeutic Single Domain Antibody (CAT#: TAB-157CL)
Recombinant Humanized monoclonal Single Domain Antibody expressed in E. coli binding to Human CEACAM6. This is an antibody specific for CEACAM6 and it may be candidates for development of antibody-based drugs against pancreatic and other cancers, one must tread carefully in the strategies targeting CEACAM6. Specifically, the monoclonal antibody alone showed no effect on tumour progression, however the same antibody conjugated to an anti-cancer drug was able to limit the tumour development in mouse model.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in a subset of leukocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/ihc_selected.jpg
(Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in a subset of leukocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/ihc_selected.jpg
Figure 2 High expression in lung.
(Macrophages Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_3_4.jpg
(Macrophages Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_3_4.jpg
Figure 3 Colon
(Enterocytes - Microvilli Staining: Medium Intensity: Moderate Mucosal lymphoid cells Staining: Medium Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_9_3.jpg
(Enterocytes - Microvilli Staining: Medium Intensity: Moderate Mucosal lymphoid cells Staining: Medium Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_9_3.jpg
Figure 4 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11041/27139_A_8_8.jpg
Figure 5 RNA cell line category: Cell line enriched (OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000086548-CEACAM6
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000086548-CEACAM6
Specifications
- Derivation
- Humanized
- Type
- Single Domain Antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- CEACAM6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); NCA; CEAL; CD66c; carcinoembryonic antigen-related cell adhesion molecule 6; normal cross-reacting antigen; Cluster of Differentiation 66c
- Gene ID
- 4680
- UniProt ID
- P40199
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CEACAM6"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1445z | Mouse Anti-CEACAM6 Recombinant Antibody (clone 29F3) | WB, IP, IF, IHC, FC | Mouse IgG1, κ |
| HPAB-N0336-YC | Human Anti-CEACAM6 Recombinant Antibody (HPAB-N0336-YC) | FC, ELISA | Humanized IgG |
| HPAB-N0045-YC | Mouse Anti-CEACAM6 Recombinant Antibody (HPAB-N0045-YC) | FC, WB, IP | Mouse IgG1, κ |
| VS-0723-WK31 | Human Anti-CEACAM6 Recombinant Antibody (clone Tinurilimab) | ELISA, FC | Human IgG2 |
| VS-0723-WK62 | Human Anti-CEACAM6 Recombinant Antibody (VS-0723-WK62) | FC | Chimeric (rabbit/human) IgG1 |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-042 | Recombinant Anti-Human CEACAM6 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-004LC-VHH | Anti-Human CEACAM6 Recombinant Antibody (2A3) | ELISA, WB, FC, Inhib, FuncS, ICC, SPR | Single domain antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-045-F(E) | Anti-Human NCA-90 Recombinant Antibody Fab Fragment(Sulesomab) | FuncS, IF, Neut, ELISA, FC, IP, IHC | Fab' - G1 |
| TAB-445LC | Mouse Anti-CEACAM6 Recombinant Antibody (TAB-445LC) | ELISA, FC, IHC | Mouse IgG1, κ |
| TAB-445LC-S(P) | Mouse Anti-CEACAM6 Recombinant Antibody; scFv Fragment (TAB-445LC-S(P)) | ELISA, FC | Mouse scFv |
| TAB-445LC-F(E) | Mouse Anti-CEACAM6 Recombinant Antibody; Fab Fragment (TAB-445LC-F(E)) | ELISA, FC | Mouse Fab |
| TAB-477MZ-S(P) | Mouse Anti-CEACAM6 Recombinant Antibody; scFv Fragment (TAB-477MZ-S(P)) | ELISA | Mouse scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-444LC-S(P) | Anti-Human CEACAM6 Recombinant Antibody scFv Fragment (NEO-Human 201) | IHC, ELISA, FC, WB | Humanized antibody |
| TAB-446LC-S(P) | Human Anti-CEACAM6 Recombinant Antibody; scFv Fragment (TAB-446LC-S(P)) | WB, IHC | Humanized scFv |
| TAB-447LC-S(P) | Human Anti-CEACAM6 Recombinant Antibody; scFv Fragment (TAB-447LC-S(P)) | WB, IHC | Humanized scFv |
| TAB-448LC-S(P) | Human Anti-CEACAM6 Recombinant Antibody; scFv Fragment (TAB-448LC-S(P)) | WB, IHC | Humanized scFv |
| TAB-449LC-S(P) | Human Anti-CEACAM6 Recombinant Antibody; scFv Fragment (TAB-449LC-S(P)) | WB, IHC | Humanized scFv |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0650 | Hi-Affi™ Rabbit Anti-CEACAM6 Recombinant Antibody (clone DS650AB) | WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0283-CN-S(P) | Human Anti-CEACAM6 Recombinant Antibody; scFv Fragment (HPAB-0283-CN-S(P)) | ELISA, WB, FC | Human scFv |
| HPAB-0284-CN-S(P) | Mouse Anti-CEACAM6 Recombinant Antibody; scFv Fragment (HPAB-0284-CN-S(P)) | ELISA, WB, FC | Mouse scFv |
| HPAB-0285-CN-S(P) | Mouse Anti-CEACAM6 Recombinant Antibody; scFv Fragment (HPAB-0285-CN-S(P)) | ELISA, WB, FC | Mouse scFv |
| HPAB-0286-CN-S(P) | Human Anti-CEACAM6 Recombinant Antibody; scFv Fragment (HPAB-0286-CN-S(P)) | ELISA, WB, FC | Humanized scFv |
| HPAB-N0045-YC-S(P) | Mouse Anti-CEACAM6 Recombinant Antibody; scFv Fragment (HPAB-N0045-YC-S(P)) | FC, WB, IP | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0283-CN-F(E) | Human Anti-CEACAM6 Recombinant Antibody; Fab Fragment (HPAB-0283-CN-F(E)) | ELISA, WB, FC | Human Fab |
| HPAB-0284-CN-F(E) | Mouse Anti-CEACAM6 Recombinant Antibody; Fab Fragment (HPAB-0284-CN-F(E)) | ELISA, WB, FC | Mouse Fab |
| HPAB-0285-CN-F(E) | Mouse Anti-CEACAM6 Recombinant Antibody; Fab Fragment (HPAB-0285-CN-F(E)) | ELISA, WB, FC | Mouse Fab |
| HPAB-0286-CN-F(E) | Human Anti-CEACAM6 Recombinant Antibody; Fab Fragment (HPAB-0286-CN-F(E)) | ELISA, WB, FC | Humanized Fab |
| HPAB-N0045-YC-F(E) | Mouse Anti-CEACAM6 Recombinant Antibody; Fab Fragment (HPAB-N0045-YC-F(E)) | FC, WB, IP | Mouse Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-157CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.