Anti-Human CXCL13 Recombinant Antibody (3D2) (CAT#: TAB-102MZ)
This antibody that specifically binds to CXCL13 may be used for treating autoimmune or inflammatory diseases, cancers, mucosa-associated lymphoid tissue (MALT) lymphomas, gastric or duodenal ulcers, as well as inhibiting gastric lymphoid follicles.
Specific Inquiry
Inhib
Figure 1 Inhibition of human CXCL13-mediated internalization of human CXCR5 receptor.
EC50 values were calculated from sigmoidal dose response curves.
IHC
Figure 2 IHC on representative spleen sections where CFSE-labeled adoptively transferred cells and B cells.
Transferred cells are green and B cells are labeled red.
FC
Figure 3 Percentage of CFSE+ B cells in mouse spleens (n = 3/group) as measured by flow cytometry.
Flow data were analyzed using FlowJo 7.6 software. Statistical significance was evaluated using unpaired Student's t-test.
FuncS
Figure 4 Effect of prophylactic and therapeutic treatment with MAb 5261-muIg on CIA progression.
Summary of the histological analysis. Statistical significance was evaluated using unpaired Student's t-test (n = 10 mice/group).
Specifications
- Immunogen
- Keyhole limpet hemocyanin (KLH)-conjugated human CXCL13
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Mouse, Cynomolgus monkey
- Clone
- 3D2
- Applications
- IHC, FuncS, FC, Inhib
- Related Disease
- Autoimmune or inflammatory diseases, cancers, mucosa-associated lymphoid tissue (MALT) lymphomas, gastric or duodenal ulcers, and gastric lymphoid follicles.
Applications
- Application Notes
- The CXCL13 antibody has been reported in applications of Inhibition, Flow Cytometry, Immunohistochemistry, Functional Assay.
Target
- Alternative Names
- CXCL13; chemokine (C-X-C motif) ligand 13; BLC; BCA1; ANGIE; BCA-1; BLR1L; ANGIE2; SCYB13; C-X-C motif chemokine 13; CXC chemokine BLC; B-cell chemoattractant; B-lymphocyte chemoattractant; b lymphocyte chemoattractant; small-inducible cytokine B13; B-cell-attracting chemokine 1; b cell-attracting chemokine 1; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); B-cell-homing chemokine (ligand for Burkitts lymphoma receptor-1); small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant)
- Gene ID
- 10563
- UniProt ID
- O43927
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2335z | Mouse Anti-CXCL13 Recombinant Antibody (clone 24G7) | WB, ELISA, FC, IHC, Neut | Mouse IgG1 |
| MOB-0904MZ | Recombinant Mouse Anti-Human CXCL13 Antibody (clone NN0323-23B3) | Neut | Mouse antibody |
| HPAB-0060-CN | Human Anti-CXCL13 Recombinant Antibody (clone Ab 1) | FC, ELISA, WB, IF | Human IgG1 |
Mouse Antibody
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-104MZ | Anti-Human CXCL13 Recombinant Antibody (MAb 1476) | ELISA | Chimeric antibody (mouse/human) |
| TAB-104MZ-S(P) | Anti-Human CXCL13 Recombinant Antibody scFv Fragment (MAb 1476) | ELISA | Chimeric antibody (mouse/human) |
| TAB-104MZ-F(E) | Anti-Human CXCL13 Recombinant Antibody Fab Fragment (MAb 1476) | ELISA | Chimeric antibody (mouse/human) |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-105MZ | Anti-Human CXCL13 Recombinant Antibody (MAb 5080) | ELISA | Humanized antibody |
| TAB-106MZ | Anti-Human CXCL13 Recombinant Antibody (MAb 5261) | ELISA | Humanized antibody |
| TAB-105MZ-S(P) | Anti-Human CXCL13 Recombinant Antibody scFv Fragment (MAb 5080) | ELISA | Humanized antibody |
| TAB-106MZ-S(P) | Anti-Human CXCL13 Recombinant Antibody scFv Fragment (MAb 5261) | ELISA | Humanized antibody |
| TAB-107MZ-S(P) | Anti-Human CXCL13 Recombinant Antibody scFv Fragment (MAb 5378) | ELISA | Humanized antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-108MZ | Anti-Human CXCL13 Recombinant Antibody | cAMP assay | Human antibody |
| TAB-110MZ | Anti-Human CXCL13 Recombinant Antibody (3B4) | ELISA | Human antibody |
| TAB-108MZ-S(P) | Anti-Human CXCL13 Recombinant Antibody scFv Fragment | cAMP assay | Human antibody |
| TAB-108MZ-F(E) | Anti-Human CXCL13 Recombinant Antibody Fab Fragment | cAMP assay | Human antibody |
| PABX-041 | Human Anti-CXCL13 Recombinant Antibody (PABX-041) | Neut, FuncS, PK, ELISA | Human IgG |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0149MZ | Chicken Anti-CXCL13 Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-613CQ | Mouse Anti-CXCL13 Recombinant Antibody (clone 12A2) | Neut, WB | Mouse IgG1 |
| NEUT-614CQ | Mouse Anti-CXCL13 Recombinant Antibody (clone MM0212-12A2) | Neut, WB | Mouse IgG1 |
| NEUT-615CQ | Mouse Anti-CXCL13 Recombinant Antibody (clone CBL037) | Neut, WB | Mouse IgG1 |
| NEUT-616CQ | Mouse Anti-CXCL13 Recombinant Antibody (clone CBL799) | WB, CyTOF®, ELISA, ICFC, Neut | Mouse IgG1 |
| NEUT-617CQ | Rat Anti-Cxcl13 Recombinant Antibody (clone 19N1) | Neut, WB | Rat IgG2 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0060-CN-S(P) | Human Anti-CXCL13 Recombinant Antibody (clone Ab 1); scFv Fragment | FC, ELISA, WB, IF | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0060-CN-F(E) | Human Anti-CXCL13 Recombinant Antibody (clone Ab 1); Fab Fragment | FC, ELISA, WB, IF | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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