Sheep Anti-CXCL14 Recombinant Antibody (clone AF730) (CAT#: HPAB-0158-LSX)
Recombinant monoclonal antibody to cxcl14. Clone AF730 is a sheep monoclonal antibody that can be potentially used in the treatment of diabetes.
Specific Inquiry
Neut
Figure 1 An anti-mouse CXCL14-specific antibody neutralizes an activity of CXCL14 inhibiting insulin signaling.
Differentiation-induced C2C12-derived myocytes were stimulated with insulin in the presence of indicated substances and phosphorylation of Akt Ser473 was determined by western blotting.
Neut
Figure 2 Data examining whether chemotaxis of forskolin-stimulated THP-1 cells to CXCL14 is neutralized by addition of an anti-mouse CXCL14-specific antibody.
After two hours of culture, the number of cells that migrated from inside to the back of the Chemotaxicell microchamber was determined to test statistical significant difference. The graph shows average value ± standard error for each group.
Neut
Figure 3 Data examining whether chemotaxis of forskolin-stimulated C2C12 cells to CXCL14 is neutralized by addition of an anti-mouse CXCL14-specific antibody.
After six hours of culture, the number of cells that migrated from inside to the back of the microchamber was determined to test statistical significant difference. The graph shows average value ± standard error for each group.
Specifications
- Host Species
- Sheep
- Type
- Sheep IgG
- Specificity
- Human CXCL14
- Species Reactivity
- Human, Mouse
- Clone
- AF730
- Applications
- WB
- Related Disease
- Diabetes
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Neutralization.
Target
- Alternative Names
- KS1; Kec; BMAC; BRAK; NJAC; MIP-2g; Scyb14; AI414372; bolekine; MIP2gamma; 1110031L23Rik; 1200006I23Rik
- Gene ID
- 57266
- UniProt ID
- Q9WUQ5
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone AF730"
See other products for "CXCL14"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2063MZ | Recombinant Mouse Anti-Human CXCL14 Antibody (clone NN0324-23C35) | WB | Mouse antibody |
| HPAB-0159-LSX | Rat Anti-CXCL14 Recombinant Antibody (clone MAB730) | WB | Rat IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0158-LSX-S(P) | Sheep Anti-CXCL14 Recombinant Antibody (clone AF730); scFv Fragment | WB | Sheep scFv |
| HPAB-0159-LSX-S(P) | Rat Anti-CXCL14 Recombinant Antibody (clone MAB730); scFv Fragment | WB | Rat scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0158-LSX-F(E) | Sheep Anti-CXCL14 Recombinant Antibody (clone AF730); Fab Fragment | WB | Sheep Fab |
| HPAB-0159-LSX-F(E) | Rat Anti-CXCL14 Recombinant Antibody (clone MAB730); Fab Fragment | WB | Rat Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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