Anti-Human FASLG Recombinant Antibody (E09) (CAT#: TAB-027WM)
A fully human anti-Fas antibody that could efficiently trigger apoptosis and therefore function as a potent agonist. And this product can be potentially used for the treatment of pemphigu.
Specific Inquiry
ELISA
Figure 1 Analysis of the 44 highest affinity E09 variant antibodies from the six selection rounds, R1-R6.
Surrogate affinity was determined using a six-point antigen titration in an ELISA-based assay.
Chodorge, M., Züger, S., Stirnimann, C., Briand, C., Jermutus, L., Grütter, M. G., & Minter, R. R. (2012). A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency. Cell death and differentiation, 19(7), 1187.
Specifications
- Immunogen
- The recombinant extracellular domain (ECD) of Fas
- Host Species
- Human
- Derivation
- Phage display
- Type
- Human Antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- E09
- Applications
- ELISA
- Related Disease
- Pemphigus
Applications
- Application Notes
- This antibody has been tested for use in ELISA. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- FASLG; Fas ligand (TNF superfamily, member 6); APTL; FASL; CD178; CD95L; ALPS1B; CD95-L; TNFSF6; APT1LG1; tumor necrosis factor ligand superfamily member 6; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1
- Gene ID
- 356
- UniProt ID
- P48023
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-025WM | Human Anti-FASLG Recombinant Antibody (TAB-025WM) | ELISA | Humanized Antibody |
| TAB-025WM-S(P) | Human Anti-FASLG Recombinant Antibody; scFv Fragment (TAB-025WM-S(P)) | ELISA | Humanized scFv |
| TAB-025WM-F(E) | Human Anti-FASLG Recombinant Antibody; Fab Fragment (TAB-025WM-F(E)) | ELISA | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-026WM | Rabbit Anti-FASLG Recombinant Antibody (TAB-026WM) | ELISA, IHC | Rabbit IgG |
| TAB-026WM-S(P) | Rabbit Anti-FASLG Recombinant Antibody; scFv Fragment (TAB-026WM-S(P)) | ELISA, IHC | Rabbit scFv |
| TAB-026WM-F(E) | Rabbit Anti-FASLG Recombinant Antibody; Fab Fragment (TAB-026WM-F(E)) | ELISA, IHC | Rabbit Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-028WM | Anti-Human FASLG Recombinant Antibody (3E1) | FC | Human Antibody |
| TAB-027WM-S(P) | Anti-Human FASLG Recombinant Antibody scFv Fragment (E09) | ELISA | Human Antibody |
| TAB-028WM-S(P) | Anti-Human FASLG Recombinant Antibody scFv Fragment (3E1) | FC | Human Antibody |
| TAB-027WM-F(E) | Anti-Human FASLG Recombinant Antibody Fab Fragment (E09) | ELISA | Human Antibody |
| TAB-028WM-F(E) | Anti-Human FASLG Recombinant Antibody Fab Fragment (3E1) | FC | Human Antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-777CQ | Mouse Anti-FASLG Recombinant Antibody (clone NOK-1) | FC, FuncS, Neut | Mouse IgG1, κ |
| NEUT-778CQ | Hamster Anti-FASLG Recombinant Antibody (clone 4H9) | ELISA, FC, Neut | Hamster IgG |
| NEUT-780CQ | Mouse Anti-FASLG Recombinant Antibody (clone CBL675) | ELISA, Neut | Mouse IgG2b |
| NEUT-781CQ | Mouse Anti-FASLG Recombinant Antibody (clone CBL256) | FC, IHC, Neut | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-779CQ | Mouse Anti-FASLG Recombinant Antibody (clone B-R17) | Block | Mouse IgG1 |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127-YC | Mouse Anti-FASLG Recombinant Antibody (clone mF919) | ELISA, FC | Mouse IgG |
| HPAB-0128-YC | Human Anti-FASLG Recombinant Antibody (clone Hu F919) | ELISA, FC | Humanized IgG |
| HPAB-0179CQ | Human Anti-FASLG Recombinant Antibody (clone 4G11) | ELISA, FC, Neut | Human IgG1, κ |
| VS3-XY666 | Mouse Anti-FASLG Recombinant Antibody, FITC (clone 4ANOK-1) | FC, IF | Mouse IgG1 |
| VS3-XY667 | Mouse Anti-FASLG Recombinant Antibody, PE (clone 4ANOK-1) | FC, IF | Mouse IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127-YC-S(P) | Mouse Anti-FASLG Recombinant Antibody (clone mF919); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0128-YC-S(P) | Human Anti-FASLG Recombinant Antibody (clone Hu F919); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-0179CQ-S(P) | Human Anti-FASLG Recombinant Antibody (clone 4G11); scFv Fragment | ELISA, FC, Neut | Human scFv |
| HPAB-2823LY-S(P) | Human Anti-FASLG Recombinant Antibody; scFv Fragment (HPAB-2823LY-S(P)) | ELISA | Human scFv |
| HPAB-2824LY-S(P) | Human Anti-FASLG Recombinant Antibody; scFv Fragment (HPAB-2824LY-S(P)) | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127-YC-F(E) | Mouse Anti-FASLG Recombinant Antibody (clone mF919); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0128-YC-F(E) | Human Anti-FASLG Recombinant Antibody (clone Hu F919); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-0179CQ-F(E) | Human Anti-FASLG Recombinant Antibody (clone 4G11); Fab Fragment | ELISA, FC, Neut | Human Fab |
| HPAB-2823LY-F(E) | Human Anti-FASLG Recombinant Antibody; Fab Fragment (HPAB-2823LY-F(E)) | ELISA | Human Fab |
| HPAB-2824LY-F(E) | Human Anti-FASLG Recombinant Antibody; Fab Fragment (HPAB-2824LY-F(E)) | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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