Mouse Anti-HBEGF Recombinant Antibody (clone HA-20) (CAT#: HPAB-0091-LS)

The antibody (clone HA-20) is a recombinant mouse antibody targeting HBEGF. HA-20 can inhibit the growth of RMG-1 cells in an antibody concentration-dependent manner. It has potential uses in the studies of pancreatic cancer, liver cancer, esophageal cancer, melanoma, and other cancers.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
ELISA

Figure 1 The binding activity of antibodies HA-20, HB-20, and HC-15 to active-form HB-EGF;

Figure 1 The binding activity of antibodies HA-20, HB-20, and HC-15 to active-form HB-EGF;

FC

Figure 2 Histograms that show the binding activity of antibodies HA-20, HB-20, and HC-15 to proHB-EGF.

Figure 2 Histograms that show the binding activity of antibodies HA-20, HB-20, and HC-15 to proHB-EGF.

Inhib

Figure 3 The inhibition of binding of HB-EGF to EGFR by antibodies HA-20, HB-20, and HC-15.

Figure 3 The inhibition of binding of HB-EGF to EGFR by antibodies HA-20, HB-20, and HC-15.

ELISA

Figure 4 Compares the inhibition of the growth of EGFR_Ba/F3 cells by antibodies HA-20, HB-20, and HC-15.

Figure 4 Compares the inhibition of the growth of EGFR_Ba/F3 cells by antibodies HA-20, HB-20, and HC-15.

Inhib

Figure 5 The inhibition of growth of the ovarian cancer cell line RMG-1 by the antibodies HA-20, HB-20, and HC-15 in a medium containing 8% FCS;

Figure 5 The inhibition of growth of the ovarian cancer cell line RMG-1 by the antibodies HA-20, HB-20, and HC-15 in a medium containing 8% FCS;

FuncS

Figure 6 The internalization-mediated activity of the HA-20, HB-20, and HC-15 antibodies to induce cell death in SKOV-3 cells (original cell line) and HB-EGF_SKOV3 cells (high HB-EGF-expressing SKOV-3 cells).

Figure 6 The internalization-mediated activity of the HA-20, HB-20, and HC-15 antibodies to induce cell death in SKOV-3 cells (original cell line) and HB-EGF_SKOV3 cells (high HB-EGF-expressing SKOV-3 cells).

FC

Figure 7 The binding activity of the HA-20, HB-20, and HC-15 antibodies for the HB-EGF on ES-2 cells.

Figure 7 The binding activity of the HA-20, HB-20, and HC-15 antibodies for the HB-EGF on ES-2 cells.

FuncS

Figure 8 The internalization-mediated cell death inducing activity of HA-20, HB-20, and HC-15, on ES-2 ovarian cancer cells.

Figure 8 The internalization-mediated cell death inducing activity of HA-20, HB-20, and HC-15, on ES-2 ovarian cancer cells.


Specifications

  • Immunogen
  • HBEGF
  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human HBEGF
  • Species Reactivity
  • Human
  • Clone
  • HA-20
  • Applications
  • Inhib, FC, ELISA, FuncS
  • Related Disease
  • Pancreatic cancer, liver cancer, esophageal cancer, melanoma

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been tested for use in Inhibition, Flow Cytometry, Enzyme-linked Immunosorbent Assay, Functional Assay.

Target

  • Alternative Names
  • DTR; DTS; DTSF; HEGFL

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone HA-20"

See other products for "HBEGF"

Humanized Antibody

CAT Product Name Application Type
TAB-340CL Anti-Human HBEGF Recombinant Antibody (KHK2866) FuncS Antibody
TAB-015CT Anti-Human HB-EGF Recombinant Antibody ELISA, Inhibition, FC Humanized antibody
TAB-015CT-S(P) Anti-Human HB-EGF Recombinant Antibody scFv Fragment ELISA, Inhibition, FC Humanized antibody
TAB-015CT-F(E) Anti-Human HB-EGF Recombinant Antibody Fab Fragment ELISA, Inhibition, FC Humanized antibody

Recombinant Antibody

CAT Product Name Application Type
HPAB-0593-CN Human Anti-HBEGF Recombinant Antibody (HPAB-0593-CN) WB, ELISA, FC, Neut Chimeric (mouse/human) IgG1
HPAB-0594-CN Human Anti-HBEGF Recombinant Antibody (HPAB-0594-CN) WB, ELISA, FC, Neut Humanized IgG1
HPAB-0092-LS Mouse Anti-HBEGF Recombinant Antibody (clone HB-20) Inhib, FC, ELISA, ADCC, FuncS Mouse IgG
HPAB-0094-LS Mouse Anti-HBEGF Recombinant Antibody (clone 8d71c81e9) ELISA, Inhib, WB, FC Mouse IgG
HPAB-0095-LS Mouse Anti-HBEGF Recombinant Antibody (clone 8d71f62f7) ELISA, Inhib, WB, FC Mouse IgG

Single-domain Antibody

CAT Product Name Application Type
HPAB-M0387-YC Recombinant Camelid Anti-HBEGF Single Domain Antibody (M/YC-25) ELISA Camelid VHH

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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