Anti-HCV E2 Recombinant Antibody (AB65) (CAT#: MRO-1206LC)
This product is a recombinant human anti-Hepatitis C virus monoclonal antibody. AB65 specifically binds to glycoprotein E2 associated with HCV and can be potentially used in the treatment and diagnosis of Hepatitis C virus infection.
Specific Inquiry
WB
Figure 1. Reactivity of HCV-AB 68 and HCV-AB 65 to E2 constructs by Western blot analysis.
Samples prepared at 37°C. Lanes: 1, His-EK-E2; 2, His-EK-E2-without HVR1; 3, E2 MCS; 4, E2 MCS without HVR1; 5, E2-CHO.
Eren, R., Landstein, D., Terkieltaub, D., Nussbaum, O., Zauberman, A., Ben-Porath, J., ... & Aviel, S. (2006). Preclinical evaluation of two neutralizing human monoclonal antibodies against hepatitis C virus (HCV): a potential treatment to prevent HCV reinfection in liver transplant patients. Journal of virology, 80(6), 2654-2664.
IP
Figure 2. Immunoprecipitation by HCV-AB 65 (in triplicates) and HBV-AB 17 as an isotype control (in triplicates).
Immunoprecipitation of virus particles from HCV-infected sera from different genotypes by HCV-AB 68 and HCV-AB 65.
Eren, R., Landstein, D., Terkieltaub, D., Nussbaum, O., Zauberman, A., Ben-Porath, J., ... & Aviel, S. (2006). Preclinical evaluation of two neutralizing human monoclonal antibodies against hepatitis C virus (HCV): a potential treatment to prevent HCV reinfection in liver transplant patients. Journal of virology, 80(6), 2654-2664.
IHC
Figure 3. HCV-AB 65 with HCV-infected liver (magnification, ×40).
Eren, R., Landstein, D., Terkieltaub, D., Nussbaum, O., Zauberman, A., Ben-Porath, J., ... & Aviel, S. (2006). Preclinical evaluation of two neutralizing human monoclonal antibodies against hepatitis C virus (HCV): a potential treatment to prevent HCV reinfection in liver transplant patients. Journal of virology, 80(6), 2654-2664.
Specifications
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Hepatitis C virus
- Clone
- AB65
- Applications
- WB, IP, IHC
- Related Disease
- Hepatitis C virus infection
Applications
- Application Notes
- The AB65 antibody has been reported in applications of WB, IHC, IP.
It's recommended that the optimal antibody concentration, dilution, incubation time etc. are best to be carefully titrated in specific assays. For details, refer to Published Data.
Target
- Alternative Names
- Hepatitis C virus; HCV; HCV E2; Hepatitis C virus E2
- Gene ID
- 951475
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-437LC | Anti-HCV E2 Recombinant Antibody (503) | ELISA | Human antibody |
| MRO-438LC | Anti-HCV E2 Recombinant Antibody (108) | ELISA | Human antibody |
| MRO-467LC | Anti-HCV E2 Recombinant Antibody (7F2) | ELISA | Human antibody |
| MRO-485LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (AB 68) | ELISA | Human antibody |
| MRO-488LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (CBH-4D) | ELISA, WB | Human antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-476LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-476LC) | ELISA, Inhib | Chimeric (mouse/human) IgG |
| MRO-476LC-S(P) | Mouse Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (MRO-476LC-S(P)) | ELISA | Mouse scFv |
| MRO-476LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-476LC-F(E)) | ELISA | Chimeric (mouse/human) Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-477LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-477LC) | ELISA | Humanized IgG1, κ |
| MRO-478LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-478LC) | ELISA | Humanized IgG1, κ |
| MRO-477LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-477LC-F(E)) | ELISA | Humanized Fab |
| MRO-478LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-478LC-F(E)) | ELISA | Humanized Fab |
| MRO-479LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-479LC-F(E)) | ELISA | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1191LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (A10F2) | ELISA | Mouse Antibody |
| MRO-1192LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (H6D3) | ELISA | Mouse Antibody |
| MRO-1193LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (E3D8) | ELISA | Mouse Antibody |
| MRO-1194LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (A7A6H9) | ELISA | Mouse Antibody |
| MRO-1195LC-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (G9E1) | ELISA | Mouse Antibody |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC428 | PE-A*24:02/HCV E2 (EYVLLLFLL) MHC Tetramer | FCM | |
| MHC-LC429 | APC-A*24:02/HCV E2 (EYVLLLFLL) MHC Tetramer | FCM |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0065LC | Recombinant Mouse Anti-HCV E2 protein Antibody (JS-81) | ELISA | IgG1 |
| EPAF-1294LC | Recombinant Human Anti-HCV E2 protein Antibody (4c2) | ELISA |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0195CQ-F(E) | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HEPC3) | ELISA, Neut | Human Fab |
| HPAB-0196CQ-F(E) | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HEPC74) | ELISA, Neut | Human Fab |
| HPAB-0197CQ-F(E) | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HEPC46) | ELISA, Neut | Human Fab |
| HPAB-0005-WJ-F(E) | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HC-84.1) | ELISA, Neut | Human Fab |
| PFBC-415 | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (PFBC-415) | ELISA, FC, Neut | Human Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-415 | Human Anti-HCV E2 Protein Recombinant Antibody (PABC-415) | ELISA, IP, Neut, Inhib, FC | Human IgG1 |
| PABC-474 | Recombinant Human Anti-HCV E2 Antibody (HCV1-C1) | ELISA, Neut | Human IgG1, κ |
| PABC-475 | Recombinant Mouse Anti-HCV E2 Antibody (MAb24) | FuncS, ELISA, Neut, IP | Mouse IgG1, κ |
| HPAB-1125-CN | Recombinant Human Anti-HCV E2 Antibody (MRCT10.1) | WB, ELISA, IF | Human IgG1, κ |
| HPAB-1126-CN | Recombinant Human Anti-HCV E2 Antibody (MRCT10.V79) | WB, ELISA, IF | Human IgG1, κ |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0085-WJ-S(P) | Mouse Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (HPAB-0085-WJ-S(P)) | ELISA, WB | Mouse scFv |
| FAMAB-0198JF-S(P) | Human Anti-HCV E2 Recombinant Antibody (clone L1); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| PSBS-0067 | Human Anti-HCV E2 Recombinant Antibody (Clone HC84-26); scFv Fragment | ELISA, FuncS | Human scFv |
| HPAB-1522WJ-S(P) | Human Anti-HCV E2 protein Recombinant Antibody; scFv Fragment (clone A8) | ELISA, WB | Human scFv |
| HPAB-1523WJ-S(P) | Human Anti-HCV E2 protein Recombinant Antibody; scFv Fragment (clone A12) | ELISA, WB | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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