Humanized Anti-Human IGHE Recombinant Antibody (clone Quilizumab) (CAT#: TAB-255)
This product is a Humanized antibody that recognizes Human IGHE. It produces crosslinking of membrane-bound IgE antigen receptors on B cells, which induces IgE+ B cell apoptosis, thereby reducing free IgE levels and inhibiting the generation of IgE+ B cells
Specific Inquiry
Specifications
- Immunogen
- IgE from myelomatous human serum.
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG1, κ
- Specificity
- Human IGHE
- Species Reactivity
- Human
- Clone
- Quilizumab
- Applications
- WB, IP, IF, FuncS, FC, Neut, ELISA
Product Property
- Purification
- Protein A Purified
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- See the COA
- Buffer
- PBS
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunoprecipitation, Immunofluorescence, Functional Assay, Flow Cytometry, Neutralization, Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- IGHE; Immunoglobulin heavy constant epsilon
- Gene ID
- 59272
Related Resources
Please refer to Quilizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Quilizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-255-S(P) | Humanized Anti-Human IGHE Recombinant Antibody (clone Quilizumab); scFv Fragment | WB, IP, IF, FuncS, FC, Neut, ELISA | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-255-F(E) | Humanized Anti-Human IGHE Recombinant Antibody (clone Quilizumab); Fab Fragment | WB, IP, IF, FuncS, FC, Neut, ELISA | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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