Recombinant monoclonal antibody to MCP-1.
Figure 1 Pharmacokinetics result.
(A) Goodness‐of‐fit plots of carlumab, free CCL2, and carlumab–CCL2 complex. (B) Comparison of predicted and observed PK/PD profiles of carlumab, free CCL2, and carlumab–CCL2 complex for the 15 mg/kg dose level.
Fetterly, G. J., Aras, U., Meholick, P. D., Takimoto, C., Seetharam, S., McIntosh, T.,... & Zhou, H. (2013). Utilizing pharmacokinetics/pharmacodynamics modeling to simultaneously examine free CCL2, total CCL2 and carlumab (CNTO 888) concentration time data. The Journal of Clinical Pharmacology, 53(10), 1020-1027.
Figure 2 Pharmacodynamics result.
a) Total CC-chemokine ligand (CCL)2 levels over time; b) free CCL2 levels over time.
Raghu, G., Martinez, F. J., Brown, K. K., Costabel, U., Cottin, V., Wells, A. U.,... & Mack, M. (2015). CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab. European Respiratory Journal, 46(6), 1740-1750.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
Afuco™ Anti-CCL2 ADCC Recombinant Antibody (Carlumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to MCP-1. Crenezumab is a humanized monoclonal antibody against human 1-40 and 1-42 Beta amyloid, which is being investigated as a treatment of Alzheimer's disease.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1273z | Mouse Anti-CCL2 Recombinant Antibody (clone 15A10) | ELISA, WB | Mouse IgG1 |
MOB-1149CT | Mouse Anti-CCL2 Recombinant Antibody (clone 2D8) | ELISA, IHC-P, sELISA | Mouse IgG1 |
HPAB-1658-FY | Mouse Anti-CCL2 Recombinant Antibody (clone C775) | ELISA | Mouse IgG1, κ |
ZG-0153U | Mouse Anti-CCL2 Recombinant Antibody (clone 3D2E5) | ELISA, IHC | Mouse IgG2b |
VS3-XY177 | Mouse Anti-CCL2 Recombinant Antibody (clone 1A7B8) | ELISA, WB | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NABG-038 | Recombinant Anti-Human CCL2 VHH Single Domain Antibody | WB, ELISA, IHC, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-418 | Human Anti-CCL2 Recombinant Antibody (clone CNTO 888); Fab Fragment | WB, ELISA, FuncS | Human Fab |
HPAB-1658-FY-S(P) | Mouse Anti-CCL2 Recombinant Antibody (clone C775); Fab Fragment | ELISA | Mouse Fab, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-418 | Human Anti-CCL2 Recombinant Antibody (clone CNTO 888); scFv Fragment | WB, ELISA, FuncS | Human scFv |
HPAB-1658-FY-F(E) | Mouse Anti-CCL2 Recombinant Antibody (clone C775); scFv Fragment | ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0744CL-F(E) | Anti-Human CCL2 Recombinant Antibody Fab Fragment (AAV293) | ELISA | |
TAB-0745CL-F(E) | Anti-Human CCL2 Recombinant Antibody Fab Fragment (AAV294) | ELISA | |
TAB-0746CL-F(E) | Mouse Anti-CCL2 Recombinant Antibody; Fab Fragment (TAB-0746CL-F(E)) | ELISA | Mouse Fab |
TAB-0747CL-F(E) | Human Anti-CCL2 Recombinant Antibody; Fab Fragment (TAB-0747CL-F(E)) | ELISA | Human Fab |
PABX-141-S (P) | Recombinant Human Anti-MCP1 Antibody scFv Fragment (cnto888) | WB, ELISA, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0748CL-F(E) | Anti-Human CCL2 Recombinant Antibody Fab Fragment (1.1.1) | ELISA | Human antibody |
TAB-0749CL-F(E) | Anti-Human CCL2 Recombinant Antibody Fab Fragment (1.10.1) | ELISA | Human antibody |
TAB-0750CL-F(E) | Anti-Human CCL2 Recombinant Antibody Fab Fragment (MC32) | ELISA | Human antibody |
TAB-0751CL-F(E) | Anti-Human CCL2 Recombinant Antibody Fab Fragment (MC8) | ELISA | Human antibody |
TAB-0752CL-F(E) | Anti-Human CCL2 Recombinant Antibody Fab Fragment (MC15) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-159CQ | Mouse Anti-CCL2 Recombinant Antibody (clone CBL254) | ELISA, IP, WB, Neut | Mouse IgG1 |
NEUT-160CQ | Mouse Anti-CCL2 Recombinant Antibody (clone CBL949) | ELISA, Neut, WB | Mouse IgG1, κ |
NEUT-161CQ | Mouse Anti-CCL2 Recombinant Antibody (clone CBL966) | ELISA, Neut, WB | Mouse IgG1, κ |
NEUT-162CQ | Rat Anti-CCL2 Recombinant Antibody (clone CBL529) | Neut | Rat IgG2b |
NEUT-163CQ | Rat Anti-CCL2 Recombinant Antibody (clone RM0172-11K27) | WB, Neut | Rat IgG2 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0504 | Hi-Affi™ Rabbit Anti-CCL2 Recombinant Antibody (clone DS504AB) | WB, IF | Rabbit IgG |
MOR-4543 | Hi-Affi™ Rabbit Anti-CCL2 Recombinant Antibody (clone TH52DS) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-117 | Afuco™ Anti-CCL2 ADCC Recombinant Antibody (Carlumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
There are currently no Customer reviews or questions for TAB-117. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.