Recombinant Mouse anti-Human TGFBR1 Monoclonal antibody (9B22) (CAT#: MOB-2021CT)
Recombinant Mouse monoclonal antibody to Human TGFBR1, expressed in Chinese Hamster Ovary cells(CHO).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/56473/985_F7_2_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/56473/985_F7_2_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows distinct cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction centra.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2441/ihc_selected.jpg
(Immunohistochemical staining of human tonsil shows distinct cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction centra.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2441/ihc_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_B_9_5.jpg
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_B_9_5.jpg
Figure 4 Cerebellum
(Cells in granular layer Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Purkinje cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_B_8_8.jpg
(Cells in granular layer Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Purkinje cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_B_8_8.jpg
Figure 5 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_A_7_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_A_7_3.jpg
Figure 6 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_A_8_5.jpg
Figure 7 RNA cell line category: Cell line enhanced (RH-30)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106799-TGFBR1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106799-TGFBR1
Specifications
- Immunogen
- Recombinant fragment corresponding to the external domain of the human TGF beta Receptor I.
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- 9B22
- Applications
- Used for immunoassay techniques such as: Immunohistochemistry paraffin embedded sections
- Conjugate
- Unconjugated
Product Property
- Purity
- Tissue culture supernatant
- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Preservative: 15mM Sodium Azide Constituents: Tissue culture supernatant
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- TGFBR1; transforming growth factor, beta receptor 1; AAT5; ALK5; ESS1; LDS1; MSSE; SKR4; ALK-5; LDS1A; LDS2A; TGFR-1; ACVRLK4; tbetaR-I; TGF-beta receptor type-1; activin receptor-like kinase 5; serine/threonine-protein kinase receptor R4; activin A receptor type II-like kinase, 53kDa; transforming growth factor-beta receptor type I; activin A receptor type II-like protein kinase of 53kD; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD);
- Gene ID
- 7046
- UniProt ID
- P36897
- Protein Refseq
- NP_001124388
- Function
- ATP binding; I-SMAD binding; SMAD binding; SMAD binding; contributes_to growth factor binding; metal ion binding; nucleotide binding; protein binding; protein heterodimerization activity; protein serine/threonine kinase activity; receptor activity; transf
Related Resources
JAK-STAT Signaling Pathway
TGF-β Signaling Pathway
Pancreatic Cancer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4032z | Mouse Anti-TGFBR1 Recombinant Antibody (clone 43H12) | WB, ELISA, IHC | Mouse IgG1 |
| ZG-0114C | Mouse Anti-TGFBR1 Recombinant Antibody (clone ABT-TGFR1) | IHC-P, IF | Mouse IgG |
| ZG-0115C | Mouse Anti-TGFBR1 Recombinant Antibody (clone ABT-TGFR2) | IHC-P, IF | Mouse IgG |
| VS3-CJ919 | Mouse Anti-TGFBR1 Recombinant Antibody (VS3-CJ919) | IHC | Mouse IgG2a |
| VS3-FY1446 | Recombinant Mouse Anti-TGFBR1 Antibody (clone 4H5-6E6-7H2) | IHC-P | Mouse IgG2a |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L077E | TGFα-PE immunotoxin | Cytotoxicity assay, Functional assay |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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