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Anti-IL-1α (Interleukin 1 alpha) Therapeutic Antibody scFv Fragment (3D12) (TAB-227CT-S(P))

Recombinant monoclonal antibody to interleukin 1 alpha. This antibody intended for the prophylaxis and treatment of Crohn's disease.      

Specifications
Immunogen
Recombinant purified human IL-1α
Host
Mouse
Specificity
Human
Species Reactivity
Human
Clone
3D12
Applications
Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Neutralization
Related Disease
Crohn's disease
Target
Alternative Names
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimers disease.
Entrez Gene ID
3552
UniProt ID
P01583

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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