Recombinant monoclonal antibody 5B11 is a human monoclonal antibody that specifically binds to human integrin α5β1 and can be potentially used in the treatment of colon cancer and pancreatic cancer.
Figure 1 A bar chart showing the effect of inhibitory α5β1 antibodies on the attachment of endothelial cells to fibronectin, in the presence of 10 μL/mL L230.
Antibody treatments are indicated on the X-axis, and compared to a no treatment control. IgG1 control, 3C5 and 5B11 were used at 10 μg/ml and 25 μg/ml as indicated. The mean cell adhesion as measured by cell count is indicated on the Y-axis, together with the standard deviation of the mean (error bars).
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-719LC-S(P) | Anti-human Integrin α5β1 scFv Fragment (3C2.2A8) | ELISA, FC | Human antibody |
TAB-720LC-S(P) | Anti-human Integrin α5β1 scFv Fragment (3C5) | ELISA, FC | Human antibody |
TAB-721LC-S(P) | Anti-human Integrin α5β1 scFv Fragment (5B11) | ELISA, FC | Human antibody |
TAB-722LC-S(P) | Anti-human Integrin α5β1 scFv Fragment (MOR04055) | ELISA, FC | Human antibody |
TAB-723LC-S(P) | Anti-human Integrin α5β1 scFv Fragment (MOR04624) | ELISA, FC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-066 | Recombinant Mouse Anti-GPIIb Antibody (314.1) | Neut, FuncS | IgG |
PABX-066-F (E) | Recombinant Mouse Anti-GPIIb Antibody Fab Fragment (314.1) | Neut, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0391-CN | Hamster Anti-Integrin α5β1 Recombinant Antibody (HPAB-0391-CN) | ELISA | Hamster IgG |
HPAB-0786-CN | Human Anti-Integrin α5β1 Recombinant Antibody (clone 2H12) | ELISA, FC | Human IgG4, κ |
HPAB-0787-CN | Human Anti-Integrin α5β1 Recombinant Antibody (clone 1F2.2B7) | ELISA, FC | Human IgG4, κ |
HPAB-0788-CN | Human Anti-Integrin α5β1 Recombinant Antibody (clone 2H12IgG1TM) | ELISA, FC | Human IgG |
HPAB-J0148-YC | Human Anti-Integrin α5β1 Recombinant Antibody (clone h18C12.v2.1) | ELISA, FuncS | Chimeric (hamster/human) IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0391-CN-S(P) | Hamster Anti-Integrin α5β1 Recombinant Antibody; scFv Fragment (HPAB-0391-CN-S(P)) | ELISA | Hamster scFv |
HPAB-0786-CN-S(P) | Human Anti-Integrin α5β1 Recombinant Antibody (clone 2H12); scFv Fragment | ELISA, FC | Human scFv |
HPAB-0787-CN-S(P) | Human Anti-Integrin α5β1 Recombinant Antibody (clone 1F2.2B7); scFv Fragment | ELISA, FC | Human scFv |
HPAB-0788-CN-S(P) | Human Anti-Integrin α5β1 Recombinant Antibody (clone 2H12IgG1TM); scFv Fragment | ELISA, FC | Human scFv |
HPAB-J0148-YC-S(P) | Human Anti-Integrin α5β1 Recombinant Antibody (clone h18C12.v2.1); scFv Fragment | ELISA, Inhib, FuncS | Hamster scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0391-CN-F(E) | Hamster Anti-Integrin α5β1 Recombinant Antibody; Fab Fragment (HPAB-0391-CN-F(E)) | ELISA | Hamster Fab |
HPAB-0786-CN-F(E) | Human Anti-Integrin α5β1 Recombinant Antibody (clone 2H12); Fab Fragment | ELISA, FC | Human Fab |
HPAB-0787-CN-F(E) | Human Anti-Integrin α5β1 Recombinant Antibody (clone 1F2.2B7); Fab Fragment | ELISA, FC | Human Fab |
HPAB-0788-CN-F(E) | Human Anti-Integrin α5β1 Recombinant Antibody (clone 2H12IgG1TM); Fab Fragment | ELISA, FC | Human Fab |
HPAB-J0148-YC-F(E) | Human Anti-Integrin α5β1 Recombinant Antibody (clone h18C12.v2.1); Fab Fragment | ELISA, Inhib, FuncS | Chimeric (hamster/human) Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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