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Recombinant Anti-KIR Antibody (CBMAB-0312MC)

Recombinant Mouse Monoclonal Antibody specifically binds to KIR2D members of the killer cell immunoglobulin (Ig)-like receptor (KIR) family, CD158a, CD158b and P50.3. KIR2D family members are cell surface glycoproteins with two Ig domains, which are expressed on natural killer cells and some T cells.
Mouse anti Human KIR antibody, clone NKVFS1 is reported to have functional activity, activating NK cell cytotoxicity via KIR2DS and inhibiting via KIR2DL forms.      

Specifications
Host
Mouse
Specificity
Mouse anti Human KIR antibody, clone NKVFS1 recognizes the long and short forms CD158a and CD158b (KIR2DL, KIR2DS1 and KIR2DS2 respectively) and also p50.3 (KIR2DS4).
Species Reactivity
Human
Target
Alternative Names
KIR2DL3; Killer cell immunoglobulin-like receptor 2DL3
Entrez Gene ID
9606
UniProt ID
P43628

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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