Recombinant monoclonal antibody 14D10 is a mouse monoclonal antibody that specifically binds to human MMP-13. The isotype of 14D10 is IgG2a.
Figure 1 Binding characteristics of the MMP-13-neutralizing antibody 14D10.
Binding of 14D10 to various MMPs was evaluated using a competitive inhibition ELISA.
Naito, S., Takahashi, T., Onoda, J., Yamauchi, A., Kawai, T., Kishino, J., ... & Numata, Y. (2012). Development of a neutralizing antibody specific for the active form of matrix metalloproteinase-13. Biochemistry, 51(44), 8877-8884.
Figure 2 Inhibition of the collagenolytic activity of human chondrocyte culture by 14D10.
Human articular chondrocytes were cultured as a monolayer on a plate coated with native type II collagen and stimulated by IL-1β and Oncostatin M to release collagenases, in the presence of the indicated concentrations of 14D10 or control IgG2b.
Naito, S., Takahashi, T., Onoda, J., Yamauchi, A., Kawai, T., Kishino, J., ... & Numata, Y. (2012). Development of a neutralizing antibody specific for the active form of matrix metalloproteinase-13. Biochemistry, 51(44), 8877-8884.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2081z | Mouse Anti-MMP13 Recombinant Antibody (clone 19A7) | WB, ICC, IF, IHC | Mouse IgG2a |
MOB-1941MZ | Recombinant Mouse Anti-Rat MMP13 Antibody (clone MJQDP JJE2), Biotin-Conjugated | ICC/IF, IP, WB | Mouse antibody |
MRO-1009-CN | Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (JF0893) | WB, IF, IHC, FC | Rabbit IgG |
VS3-WK1856 | Recombinant Rabbit Anti-MMP13 Capture Antibody (clone R73-2Z-9) | ELISA | Rabbit IgG |
VS3-WK1857 | Recombinant Rabbit Anti-MMP13 Detection Antibody (clone R78-6T-5) | ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0820CL | Human Anti-MMP13 Recombinant Antibody (TAB-0820CL) | ELISA, IHC | Human IgG |
TAB-0821CL | Human Anti-MMP13 Recombinant Antibody (TAB-0821CL) | ELISA, IHC | Human IgG |
TAB-0820CL-S(P) | Human Anti-MMP13 Recombinant Antibody; scFv Fragment (TAB-0820CL-S(P)) | ELISA, IHC | Human scFv |
TAB-0821CL-S(P) | Human Anti-MMP13 Recombinant Antibody; scFv Fragment (TAB-0821CL-S(P)) | ELISA, IHC | Human scFv |
TAB-0820CL-F(E) | Human Anti-MMP13 Recombinant Antibody; Fab Fragment (TAB-0820CL-F(E)) | ELISA, IHC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0819CL-S(P) | Anti-Human MMP13 Recombinant Antibody scFv Fragment (14D10) | ELISA | |
TAB-0819CL-F(E) | Anti-Human MMP13 Recombinant Antibody Fab Fragment (14D10) | ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0369MZ | Chicken Anti-MMP13 Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2250 | Hi-Affi™ Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (DS2250AB) | WB | IgG |
MOR-4649 | Hi-Affi™ Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (TH162DS) | WB, IF, ICC, IHC-P, FC | IgG |
There are currently no Customer reviews or questions for TAB-0819CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.